Definition

Peritonitis is an inflammation or infection of the peritoneum. The peritoneum is a thin tissue lining that covers the inside of the abdominal cavity. It also covers the outside of the intestines and other abdominal organs.

There are several types:

  • Primary
  • Secondary
  • Peritoneal dialysis related

Peritonitis is a serious condition. It requires immediate treatment. If not promptly treated, it can be fatal.

Causes

Primary peritonitis—occurs when there is a buildup of fluid in the abdomen. This is called ascites. It is caused by chronic liver disease, among other conditions.

Secondary peritonitis—caused by bacteria that enter the abdominal cavity. Can be due to an injury or a condition, such as a ruptured appendix.

Secondary Peritonitis

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Dialysis-related peritonitis—caused by bacteria that enter the peritoneal cavity during or after peritoneal dialysis (a treatment for kidney disease).

Risk Factors

A risk factor is something that increases your chance of getting a disease or condition. Risk factors for peritonitis include:

Symptoms

Symptoms may include:

  • Severe pain or tenderness in the abdomen
  • Pain in the abdomen that is worse with motion
  • Bloating of the abdomen
  • Constipation
  • Fever
  • Nausea and vomiting
  • Weakness or dizziness
  • Shortness of breath
  • Rapid pulse or breathing rate
  • Dehydration—signs include dry skin and lips, decreased urine production

Diagnosis

The doctor will ask about your symptoms and medical history, and perform a physical exam. Tests may include:

  • Blood tests
  • Analysis of fluids from the peritoneum
  • Abdominal x-rays to look for signs of inflammation
  • Laparotomy—surgery to open and examine the abdomen

Treatment

Treatment depends on the cause. It may include:

  • Surgery to repair openings in the skin surface or to remove damaged tissue
  • Antibiotics to treat infection
  • Replacement of fluids

Prevention

There are no guidelines for preventing peritonitis.